New bad dating anywhere between ? and you may ? remains tall once handling on influence out of CO rates [semi-limited correlation roentgen = ?0
c and ? considering one hundred-kb adjoining screen having window classified toward six kinds of equivalent matter predicated on c [CO1, Co2, . CO6 exhibiting expanding rates off c] The typical c (cM/Mb/female meiosis) values with the half a dozen categories is: 0.078 (CO1), 0.727 (CO2), step one.439 (CO3), 2.294 (CO4), step 3.299 (CO5) and you may 5.964 (CO6). Bluish articles work when whole chromosomes is assessed. Lime columns work immediately following removing centromeric and you will telomeric places having substantially less CO pricing. 1246 (P = step one.6?10 ?5 ) to have entire chromosomes and you can Roentgen = ?0.1191 (P = 1.2?ten ?4 ) immediately following removing telomeric/centromeric countries.
Several hypotheses can be put forward to explain the other surface getting CO and you will GC over the D. melanogaster genome. Divergent DSB fix paths have been recommended from inside the Drosophila as with fungus , , having a good synthesis-centered strand annealing (SDSA) pathway that is related only with GC situations, once the quality of double Holliday junction (DHJ) can be Thai dating app reviews make often CO otherwise GC (Shape S1). The brand new recognition off GC incidents regarding the fourth chromosome highly implies the action from SDSA, about to possess good chromosome entirely lacking CO, and demonstrates that SDSA are acting over the whole genome. Fortsett å lese There can be a critical negative dating ranging from c and ? having fun with independent (non-overlapping) 100-kb screen: Spearman’s Roentgen = ?0